Article
High sodium intake modulates left ventricular mass in patients with G expression of +1675 G/A angiotensin II receptor type 2 gene.
Journal of hypertension - 1 Aug 2007
Ott Christian, Titze Stephanie I, Schwarz Thomas K, Kreutz Reinhold, Hilgers Karl F, Schmidt Bernhard M W, Schlaich Markus P, Schmieder Roland E
Abstract excerpt
OBJECTIVES: In patients with hypertension left ventricular hypertrophy (LVH) is associated with genetic variations of the angiotensin type 2 receptor (AT2R). Hypertension and LVH are often aggravated by salt intake. Our objective was to assess the relationship between AT2R gene variation and salt intake and their impact on left ventricular mass (LVM). METHODS AND RESULTS: In 205 subjects with normal or mildly...
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