Article
Can angiotensin II +1675 G/A type 2 receptor gene polymorphism be a marker of left ventricular hypertrophy in patients with aortic stenosis?
The Journal of heart valve disease - 1 Sept 2007
Orlowska-Baranowska Ewa, Placha Grzegorz, Baranowski Rafal, Michalek Piotr, Gora Jarosław, Gaciong Zbigniew, Stepinska Janina
Abstract excerpt
BACKGROUND AND AIM OF THE STUDY: Activation of the angiotensin II type 2 receptor (AT2R) gene lowers blood pressure, inhibits endothelial and smooth muscle proliferation, and modifies left ventricular hypertrophy (LVH) and fibrosis. Recently, several studies on the presence and importance of AT2R polymorphism for cardiovascular pathology have been reported. The study aim was to investigate any relationship...
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