Article
Angiotensin II type 2 receptor gene polymorphism and cardiovascular phenotypes: the GLAECO and GLAOLD studies.
European journal of heart failure - 1 Dec 2002
Herrmann Stefan-Martin, Nicaud Viviane, Schmidt-Petersen Klaus, Pfeifer Jacqueline, Erdmann Jeanette, McDonagh Theresa, Dargie Henry J, Paul Martin, Regitz-Zagrosek Vera
Abstract excerpt
BACKGROUND: The angiotensin II type 2 (AT2) receptor is thought to play a role in cardiovascular disorders such as neointima formation after vascular injury, cardiac hypertrophy and myocardial infarction (MI). Recently, the biallelic polymorphism G + 1675A in intron 1 of the AT2 receptor gene has been associated with left ventricular posterior, septal and relative wall thickness, as well as left ventricular mass...
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