Article
Left ventricle mass index and the common, functional, X-linked angiotensin II type-2 receptor gene polymorphism (-1332 G/A) in patients with systemic hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Jun 2004
Alfakih Khaled, Maqbool Azhar, Sivananthan Mohan, Walters Kevin, Bainbridge Gavin, Ridgway John, Balmforth Anthony J, Hall Alistair S
Abstract excerpt
A common intronic polymorphism, (-1332 G/A) of the angiotensin type-2 receptor gene, located on the X-chromosome, has been reported to be functional. The aim of our study was to evaluate this polymorphism for an association with left ventricular hypertrophy. Left ventricle (LV) mass was measured in 197 patients with systemic hypertension and 60 normal volunteers using a 1.5-Tesla Philips MRI system. Genotyping...
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