Article
Aldosterone synthase (CYP11B2) -344 C/T polymorphism is associated with left ventricular structure in human arterial hypertension.
Journal of the American College of Cardiology - 1 Mar 2001
Delles C, Erdmann J, Jacobi J, Hilgers K F, Fleck E, Regitz-Zagrosek V, Schmieder R E
Abstract excerpt
OBJECTIVES: This study examined the association between the -344 C/T polymorphism of the human aldosterone synthase promoter and left ventricular structure in arterial hypertension. BACKGROUND: Because of conflicting results from different studies, the mechanism of such an association, if any, has not been determined. METHODS: We examined the aldosterone synthase promoter genotype in 120 young (age: 26 +/- 3...
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