Article
Role of the angiotensin II type 2 receptor gene (+1675G/A) polymorphism on left ventricular hypertrophy and geometry in treated hypertensive patients.
Journal of hypertension - 1 Jun 2010
Huber Matthias, Völler Heinz, Jakob Stefanie, Reibis Rona, Do Van, Bolbrinker Juliane, Zergibel Irina, Schmieder Roland E, Treszl Andras, Wegscheider Karl, Kreutz Reinhold
Abstract excerpt
OBJECTIVE: A genetic polymorphism in the angiotensin II type 2 receptor (AGTR2 +1675G/A) has been associated with left ventricular hypertrophy (LVH). We tested whether this polymorphism affects LVH and left ventricular geometry parameters in patients with essential hypertension and cardiovascular disease who are treated according to guidelines. METHODS: We analyzed a cohort of 208 women and 1030 men with...
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