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Article

Associations between human aldosterone synthase (CYP11B2) gene polymorphisms and left ventricular size, mass, and function.

Circulation - 17 Feb 1998

Kupari M, Hautanen A, Lankinen L, Koskinen P, Virolainen J, Nikkila H, White P C

Abstract excerpt

BACKGROUND: Aldosterone has direct and indirect effects on the heart, and genetic variations in aldosterone synthesis could therefore influence cardiac structure and function. Such variations might be associated with polymorphisms in the gene encoding aldosterone synthase (CYP11B2), the enzyme catalyzing the last steps of aldosterone biosynthesis. METHODS AND RESULTS: A Finnish population sample of 84 persons (44...

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Share to Cytochrome P-450 CYP11B2
Share to Echocardiography

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Heart Ventricles

Share to Polymorphism, Genetic

Share to Regression Analysis

Share to Sodium, Dietary

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Source

Identifiers

PMID: 9494027
DOI: 10.1161/01.cir.97.6.569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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