Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in angiotensin II type 2 receptor gene influences extent of left ventricular hypertrophy in hypertrophic cardiomyopathy independent of blood pressure.

Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Sept 2011

Carstens Nadia, van der Merwe Lize, Revera Miriam, Heradien Marshall, Goosen Althea, Brink Paul A, Moolman-Smook Johanna C

Abstract excerpt

INTRODUCTION: Hypertrophic cardiomyopathy (HCM), an inherited primary cardiac disorder mostly caused by defective sarcomeric proteins, serves as a model to investigate left ventricular hypertrophy (LVH). HCM manifests extreme variability in the degree and distribution of LVH, even in patients with the same causal mutation. Genes coding for renin-angiotensin-aldosterone system components have been studied as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Pressure
Share to Cardiomyopathy, Hypertrophic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Gene Frequency

Share to Heart Ventricles

Share to Hypertrophy, Left Ventricular

Share to Principal Component Analysis

Share to Receptor, Angiotensin, Type 2

Source

Identifiers

PMID: 21163866
DOI: 10.1177/1470320310390725

Genes

AGTR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in angiotensin II type 2 receptor gene influences extent of left ventricular hypertrophy in hypertrophic cardiomyopathy independent of blood pressure.PMID 21163866Read ↗

Impact of polymorphisms in the renin-angiotensin-aldosterone system on hypertrophic cardiomyopathy.Semantic proximity Read ↗

Genetic variation in angiotensin-converting enzyme 2 gene is associated with extent of left ventricular hypertrophy in hypertrophic cardiomyopathy.Semantic proximity Read ↗

Hypertrophy-associated polymorphisms ascertained in a founder cohort applied to heart failure risk and mortality.Semantic proximity Read ↗

Hypertrophic remodelling in cardiac regulatory myosin light chain (MYL2) founder mutation carriers.Semantic proximity Read ↗

Role of the angiotensin II type 2 receptor gene (+1675G/A) polymorphism on left ventricular hypertrophy and geometry in treated hypertensive patients.Semantic proximity Read ↗

Angiotensin II type 2 receptors and cardiac hypertrophy in women with hypertrophic cardiomyopathy.Semantic proximity Read ↗

Genetic variants predicting left ventricular hypertrophy in a diabetic population: a Go-DARTS study including meta-analysis.Semantic proximity Read ↗

Genes for left ventricular hypertrophy.Semantic proximity Read ↗

Hypertensive cardiac hypertrophy--is genetic variance the missing link?Semantic proximity Read ↗

The role of genetic variants in angiotensin I converting enzyme, angiotensinogen and the angiotensin II type-1 receptor in the pathophysiology of heart muscle disease.Semantic proximity Read ↗

Cardiac aldosterone in subjects with hypertrophic cardiomyopathy.Semantic proximity Read ↗

The Burden of Early Phenotypes and the Influence of Wall Thickness in Hypertrophic Cardiomyopathy Mutation Carriers: Findings From the HCMNet Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.