Association of echocardiographic left ventricular structure and -344C/T aldosterone synthase gene variant: A meta-analysis.

doi:10.1177/1470320314535459

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Article

Association of echocardiographic left ventricular structure and -344C/T aldosterone synthase gene variant: A meta-analysis.

Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2015

Wang Lijuan, Zhou Jiapeng, Zhang Bei, Wang Hao, Li Mei, Niu Qiuli, Chen Yubao, Chen Runsheng, Wen Shaojun

Abstract excerpt

BACKGROUND: Aldosterone synthase (CYP11B2) is one of the most studied candidate genes related to essential hypertension (EH) and left ventricular hypertrophy (LVH). Some studies have focused on the relationship between -344C/T polymorphism (rs1799998) in the CYP11B2 gene and LVH, but the results are controversial. This meta-analysis is purposed to reveal the relationship between the -344C/T and the left...

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PMID: 25208931
DOI: 10.1177/1470320314535459

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