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Article

Inactivation of MMAC1 in bladder transitional-cell carcinoma cell lines and specimens.

Molecular carcinogenesis - 1 Nov 2000

Liu J, Babaian D C, Liebert M, Steck P A, Kagan J

Abstract excerpt

We recently limited the location of a candidate tumor suppressor gene in invasive (T3a/b) bladder transitional-cell carcinoma (TCC) to a 2.5-cM region at chromosome 10q23.3. This region harbors the MMAC1/PTEN/TEP1 gene (referred to hereafter as MMAC1), a dual-phosphatase tumor-suppressor gene frequently inactivated in variety of malignant tumors. In the present study, we examined whether MMAC1 is a target for...

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Share to Carcinoma, Transitional Cell
Share to Gene Rearrangement
Share to Gene Silencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phosphoric Monoester Hydrolases

Share to Polymorphism, Single-Stranded Conformational

Share to PTEN Phosphohydrolase

Share to Tumor Suppressor Proteins

Share to Urinary Bladder Neoplasms

Source

Identifiers

PMID: 11108659
DOI: 10.1002/1098-2744(200011)29:3<143::aid-mc3>3.0.co;2-a

Genes

PTEN
TEP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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