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Article

Somatic mutation of PTEN in bladder carcinoma.

British journal of cancer - 1 May 1999

Aveyard J S, Skilleter A, Habuchi T, Knowles M A

Abstract excerpt

The tumour suppressor gene PTEN/MMAC1, which is mutated or homozygously deleted in glioma, breast and prostate cancer, is mapped to a region of 10q which shows loss of heterozygosity (LOH) in bladder cancer. We screened 123 bladder tumours for LOH in the region of PTEN. In 53 informative muscle i...

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Topics

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Share to Carcinoma, Transitional Cell
Share to Chromosomes, Human, Pair 10
Share to Genes, Tumor Suppressor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Loss of Heterozygosity

Share to Phosphoric Monoester Hydrolases

Share to Polymorphism, Single-Stranded Conformational

Share to PTEN Phosphohydrolase

Share to Urinary Bladder Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 10360673
DOI: 10.1038/sj.bjc.6690439
PMCID: PMC2362287

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10360673-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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