Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spontaneous fracture (sfx): a mouse genetic model of defective peripubertal bone formation.

Bone - 1 Nov 2000

Beamer W G, Rosen C J, Bronson R T, Gu W, Donahue L R, Baylink D J, Richardson C C, Crawford G C, Barker J E

Abstract excerpt

A new mouse model of stage-specific bone growth failure and fracture has been recovered as an autosomal recessive mutation, designated spontaneous fracture (sfx). The sfx/sfx mice are phenotypically normal until shortly after weaning, when reduced mobility and impaired somatic growth are first no...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Development
Share to Bone fractures and treatments
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

Share to Models, Genetic

Share to Mutation

Share to Phenotype

Source

Identifiers

PMID: 11062347
DOI: 10.1016/s8756-3282(00)00369-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11062347-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spontaneous fracture (sfx): a mouse genetic model of defective peripubertal bone formation.PMID 11062347Read ↗

Spontaneous fractures in the mouse mutant sfx are caused by deletion of the gulonolactone oxidase gene, causing vitamin C deficiency.Semantic proximity Read ↗

A deletion causing spontaneous fracture identified from a candidate region of mouse Chromosome 14.Semantic proximity Read ↗

Osteoblast-Specific Expression of the Fibrous Dysplasia (FD)–Causing Mutation <i>GsαR201C</i> Produces a High Bone Mass Phenotype but Does Not Reproduce FD in the MouseSemantic proximity Read ↗

Morphological and mechanical characterization of bone phenotypes in the Amish G610C murine model of osteogenesis imperfecta.Semantic proximity Read ↗

Skeletal Site-specific Changes in Bone Mass in a Genetic Mouse Model for Human 15q11-13 Duplication Seen in Autism.Semantic proximity Read ↗

Rapid phenotyping of knockout mice to identify genetic determinants of bone strength.Semantic proximity Read ↗

Skeletal Malformations Caused by Overexpression of Cbfa1 or Its Dominant Negative Form in ChondrocytesSemantic proximity Read ↗

Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3.Semantic proximity Read ↗

Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength.Semantic proximity Read ↗

Deletion of Tfam in Prx1-Cre expressing limb mesenchyme results in spontaneous bone fracturesSemantic proximity Read ↗

Phenotypic characterization of Slc26a2 mutant mice reveals a multifactorial etiology of spondylolysis.Semantic proximity Read ↗

Genetic variation in bone growth patterns defines adult mouse bone fragility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.