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Article

A general test of association for complex diseases with variable age of onset.

Genetic epidemiology - 1 Jan 2000

Li H, Fan J

Abstract excerpt

Analysis of age of onset is a key factor in linkage and association studies of some complex genetic traits. Recent methodological developments are mainly concentrated on binary or quantitative traits, in which age of onset information is ignored. We propose a linkage disequilibrium-based Cox model and a robust score test for testing association between a marker and a disease with variable age of onset. The...

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Identifiers

PMID: 11055369
DOI: 10.1002/1098-2272(2000)19:1+<::AID-GEPI7>3.0.CO;2-J

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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