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Article

Genetic association tests with age at onset.

Genetic epidemiology - 1 Feb 2003

Hsu L

Abstract excerpt

Many diseases or traits exhibit a varying age at onset. Recent data examples of prostate cancer and childhood diabetes show that compared to simply treating the disease outcome as affected vs. unaffected, incorporation of age-at-onset information into the transmission/disequilibrium type of test (TDT) does not appear to change the results much. In this paper, we evaluate the power of TDT as a function of age at...

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PMID: 12548673
DOI: 10.1002/gepi.10210

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