Article
Apolipoprotein E in Southern Italy: protective effect of epsilon 2 allele in early- and late-onset sporadic Alzheimer's disease.
Neuroscience letters - 6 Oct 2000
Panza F, Solfrizzi V, Torres F, Mastroianni F, Colacicco A M, Basile A M, Capurso C, D'Introno A, Del Parigi A, Capurso A
Abstract excerpt
Apolipoprotein E (apoE) polymorphism was evaluated in 81 sporadic late onset Alzheimer's disease (LOAD) patients, 28 sporadic early-onset Alzheimer's disease (EOAD) and 92 sex- and age-matched healthy controls from Apulia, Southern Italy. ApoE genotypes were determined by the polymerase chain reaction-restriction fragment length polymorphism method. The frequency of apoE epsilon 4 allele was significantly higher...
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