Article
Association of apolipoprotein E epsilon 4 allele with sporadic late onset Alzheimer`s disease. A meta-analysis.
Neurosciences (Riyadh, Saudi Arabia) - 1 Oct 2012
Sadigh-Eteghad Saeed, Talebi Mahnaz, Farhoudi Mehdi
Abstract excerpt
OBJECTIVE: To obtain a better insight into the effect of the epsilon (e) 4 allele of the apolipoprotein E gene (APOE) on the risk of late onset Alzheimer`s disease (LOAD), and assess its heterogeneity in geographic regions. METHODS: We performed a systemic review and meta-analysis of available studies. An electronic and manual search of international and local databases was conducted to identify relevant studies...
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