Article
Apolipoprotein E and Alzheimer disease: genotype-specific risks by age and sex.
American journal of human genetics - 1 Feb 1997
Bickeböller H, Campion D, Brice A, Amouyel P, Hannequin D, Didierjean O, Penet C, Martin C, Pérez-Tur J, Michon A, Dubois B, Ledoze F, Thomas-Anterion C, Pasquier F, Puel M, Demonet J F, Moreaud O, Babron M C, Meulien D, Guez D, Chartier-Harlin M C, Frebourg T, Agid Y, Martinez M, Clerget-Darpoux F
Abstract excerpt
The distribution of apolipoprotein E (APOE) genotypes as a function of age and sex has been examined in a French population of 417 Alzheimer disease (AD) patients and 1,030 control subjects. When compared to the APOE epsilon3 allele, an increased risk associated with the APOE epsilon4 allele (odd...
Topics
- Age of Onset
- Aged
- Aged, 80 and over
- Aging
- Alzheimer Disease
- Apolipoprotein E2
- Apolipoprotein E3
- Apolipoprotein E4
- Apolipoproteins E
- Case-Control Studies