Article
Apolipoprotein E polymorphism and Alzheimer's disease in eastern Finland.
Neuroscience letters - 6 Feb 1995
Lehtovirta M, Helisalmi S, Mannermaa A, Soininen H, Koivisto K, Ryynänen M, Riekkinen P
Abstract excerpt
Apolipoprotein E is a polymorphic protein defined by three alleles, epsilon 2, epsilon 3 and epsilon 4. An increased frequency of the epsilon 4 allele is associated with late-onset familial and sporadic Alzheimer's disease (AD). We studied 202 Finnish AD patients and 55 age- and sex-matched contr...
Topics
- Age of Onset
- Aged
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Chromosomes, Human, Pair 19
- Female
- Finland
- Genotype
- Humans
- Male