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Article

Structural analysis of yeast HSF by site-specific crosslinking.

Journal of molecular biology - 22 Sept 2000

Bonner J J, Chen D, Storey K, Tushan M, Lea K

Abstract excerpt

We have introduced cysteine substitutions into the yeast HSF1 gene at a variety of locations. Most have no phenotypic effect, and therefore provide site-specific probes for thiol-specific reagents. Crosslinking of single mutants identifies locations where equivalent regions of individual monomers can approach each other in the HSF trimer. Crosslinking of double mutants indicates regions that can approach closely...

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Source

Identifiers

PMID: 10986120
DOI: 10.1006/jmbi.2000.4096

Genes

HSF1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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