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Article

Mutated yeast heat shock transcription factor activates transcription independently of hyperphosphorylation.

The Journal of biological chemistry - 17 Feb 2006

Hashikawa Naoya, Mizukami Yu, Imazu Hiromi, Sakurai Hiroshi

Abstract excerpt

The homotrimeric heat shock transcription factor (HSF) binds to the heat shock element of target genes and regulates transcription in response to various stresses. The Hsf1 protein of Saccharomyces cerevisiae is extensively phosphorylated upon heat shock; a modification that is under positive regulation by its C-terminal regulatory domain (CTM). Hyperphosphorylation has been implicated in gene-specific...

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Identifiers

PMID: 16361698
DOI: 10.1074/jbc.M510827200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutated yeast heat shock transcription factor activates transcription independently of hyperphosphorylation.PMID 16361698Read ↗

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