Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The DNA-binding domain of yeast Hsf1 regulates both DNA-binding and transcriptional activities.

Biochemical and biophysical research communications - 11 Aug 2006

Yamamoto Ayako, Sakurai Hiroshi

Abstract excerpt

The heat shock transcription factor (HSF) is a key regulator of the heat shock response. In Saccharomyces cerevisiae, the transcription activating ability of Hsf1 is repressed by its DNA-binding domain, but the detailed mechanism by which the inhibitory function is relieved in response to stress remains unknown. In this study, we isolated and characterized three hsf1 mutants with temperature-sensitive mutations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Heat-Shock Proteins

Share to Protein Structure, Tertiary

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to Temperature

Share to Transcription, Genetic

Source

Identifiers

PMID: 16806072
DOI: 10.1016/j.bbrc.2006.06.057

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The DNA-binding domain of yeast Hsf1 regulates both DNA-binding and transcriptional activities.PMID 16806072Read ↗

Identification of a novel class of target genes and a novel type of binding sequence of heat shock transcription factor in Saccharomyces cerevisiae.Semantic proximity Read ↗

The DNA-binding domain of yeast heat shock transcription factor independently regulates both the N- and C-terminal activation domains.Semantic proximity Read ↗

Mutated yeast heat shock transcription factor activates transcription independently of hyperphosphorylation.Semantic proximity Read ↗

Temperature-dependent regulation of a heterologous transcriptional activation domain fused to yeast heat shock transcription factor.Semantic proximity Read ↗

A Heat Shock-Responsive Domain of Human HSF1 That Regulates Transcription Activation Domain FunctionSemantic proximity Read ↗

Mutational analysis of human heat-shock transcription factor 1 reveals a regulatory role for oligomerization in DNA-binding specificity.Semantic proximity Read ↗

Mutations in the Schizosaccharomyces pombe heat shock factor that differentially affect responses to heat and cadmium stress.Semantic proximity Read ↗

Activation of the Saccharomyces cerevisiae heat shock transcription factor under glucose starvation conditions by Snf1 protein kinase.Semantic proximity Read ↗

Knocking down gene function with an RNA aptamer expressed as part of an intron.Semantic proximity Read ↗

Arabidopsis HsfB1 and HsfB2b act as repressors of the expression of heat-inducible Hsfs but positively regulate the acquired thermotolerance.Semantic proximity Read ↗

Arabidopsis HsfA1 transcription factors function as the main positive regulators in heat shock-responsive gene expression.Semantic proximity Read ↗

Carboxy-terminal region of the yeast heat shock factor contains two domains that make transcription independent of the TFIIH protein kinase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.