Article
Modulation of human heat shock factor trimerization by the linker domain.
The Journal of biological chemistry - 11 Jun 1999
Liu P C, Thiele D J
Abstract excerpt
Heat shock transcription factors (HSFs) are stress-responsive proteins that activate the expression of heat shock genes and are highly conserved from bakers' yeast to humans. Under basal conditions, the human HSF1 protein is maintained as an inactive monomer through intramolecular interactions be...
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