Article
Association analyses of endothelial nitric oxide synthase gene polymorphisms in essential hypertension.
American journal of hypertension - 1 Sept 2000
Benjafield A V, Morris B J
Abstract excerpt
Endothelial nitric oxide synthase (eNOS), encoded by NOS3, is a potent regulator of vasomotor tone and peripheral resistance. Congenic experiments indicate that a chromosomal segment containing the rat eNOS gene contributes to rat spontaneous hypertension (HT). A role for NOS3 in onset of essential hypertension (HT) is, however, controversial. We therefore decided to test NOS3 polymorphisms in a set of patients...
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