Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Endothelial nitric oxide synthase gene polymorphisms and cardiovascular disease: a HuGE review.

American journal of epidemiology - 15 Nov 2006

Casas Juan P, Cavalleri Gianpiero L, Bautista Leonelo E, Smeeth Liam, Humphries Steve E, Hingorani Aroon D

Abstract excerpt

This review examines the association of a subset of endothelial nitric oxide synthase gene (NOS3) polymorphisms (Glu298Asp, intron 4, and -786T>C) with cardiovascular disease. The Glu298Asp polymorphism within exon 7 is the only common nonsynonymous variant. The variants have been associated with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular Diseases
Share to NOS3 gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Genotype

Share to Nitric Oxide Synthase Type III

Share to Polymorphism, Genetic

Share to Risk Factors

Source

Identifiers

PMID: 17018701
DOI: 10.1093/aje/kwj302

Genes

NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17018701-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Endothelial nitric oxide synthase gene polymorphisms and cardiovascular disease: a HuGE review.PMID 17018701Read ↗

Endothelial nitric oxide synthase gene polymorphisms in cardiovascular disease.Semantic proximity Read ↗

Association Patterns of Endothelial Nitric Oxide Synthase Gene (NOS3) Variant Glu298Asp with Blood Pressure and Serum Lipid Levels in Subjects with Coronary Artery Disease from Pakistan.Semantic proximity Read ↗

Association of endothelial nitric oxide synthase gene polymorphisms with coronary artery disease: an updated meta-analysis and systematic review.Semantic proximity Read ↗

Therapeutic implications of human endothelial nitric oxide synthase gene polymorphism.Semantic proximity Read ↗

Endothelial nitric oxide synthase: From biochemistry and gene structure to clinical implications of NOS3 polymorphisms.Semantic proximity Read ↗

Glu298Asp variant of the endothelial nitric oxide synthase gene and acute coronary syndrome or premature coronary artery disease: A systematic review and meta-analysis.Semantic proximity Read ↗

Endothelial nitric oxide synthase gene: prospects for treatment of heart disease.Semantic proximity Read ↗

Endothelial nitric oxide synthase (eNOS) variants in cardiovascular disease: pharmacogenomic implications.Semantic proximity Read ↗

Prevalence of endothelial nitric oxide synthase (eNOS) gene exon 7 Glu298Asp variant in North Eastern India.Semantic proximity Read ↗

Clinical and pharmacogenetic impact of endothelial nitric oxide synthase polymorphisms on cardiovascular diseasesSemantic proximity Read ↗

Clinically relevant endothelial nitric oxide synthase polymorphisms and their impact on drug response.Semantic proximity Read ↗

Glu298Asp endothelial nitric oxide synthase gene polymorphism interacts with environmental and dietary factors to influence endothelial function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.