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Genetic and Pharmacogenetic Associations Between NOS3 Polymorphisms, Blood Pressure, and Cardiovascular Events in Hypertension

30 Apr 2009

Abstract excerpt

BACKGROUND: Polymorphisms in the endothelial nitric oxide synthase (NOS3) gene increase susceptibility to hypertension and cardiovascular disease. We examined genetic and pharmacogenetic associations between NOS3 polymorphisms, blood pressure (BP) control, and cardiovascular events in elderly, hypertensive coronary artery disease (CAD) patients. METHODS: Patients with CAD were randomly assigned to either...

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PMID: 19407804
DOI: 10.1038/ajh.2009.81

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