Article
Endothelial nitric oxide synthase gene (NOS3) variant and hypertension in pregnancy.
American journal of medical genetics - 15 Oct 2001
Kobashi G, Yamada H, Ohta K, Kato E, Ebina Y, Fujimoto S
Abstract excerpt
Hypertension in pregnancy (HP), including preeclampsia, is known to be a multifactorial disease. Recently, a Glu298Asp variant of the endothelial nitric oxide synthase gene (NOS3) was identified as being associated with coronary spasm and myocardial infarction, whereas it has been reported that endothelial nitric oxide synthase plays a role in HP. We therefore performed an association study of the Glu298Asp...
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