Article
Association of NOS3 gene polymorphisms with essential hypertension in Sudanese patients: a case control study.
BMC medical genetics - 13 Nov 2017
Gamil Sahar, Erdmann Jeanette, Abdalrahman Ihab B, Mohamed Abdelrahim O
Abstract excerpt
BACKGROUND: Essential hypertension (EH) is influenced by various environmental and genetic factors. Nitric oxide is important for the functional integrity of the vascular endothelium and is produced in endothelial cells by the enzyme endothelial nitric oxide synthase (eNOS). EH has a strong genetic component, and the NOS3 gene, which encodes eNOS, represents an interesting candidate for contribution to the...
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