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Article

Therapeutic implications of human endothelial nitric oxide synthase gene polymorphism.

Trends in pharmacological sciences - 1 Jul 2001

Wattanapitayakul S K, Mihm M J, Young A P, Bauer J A

Abstract excerpt

Vascular endothelial dysfunction is now recognized as a common phenomenon in an array of cardiovascular disorders. Production of nitric oxide via the endothelial isoform of nitric oxide synthase [eNOS (previously termed NOS3 or ecNOS)] is vital for a healthy endothelium; several polymorphic variations of the gene encoding eNOS (NOS3) are now known and have been investigated with respect to disease risk....

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Source

Identifiers

PMID: 11431031
DOI: 10.1016/s0165-6147(00)01692-8

Genes

NOS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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