Article
Endothelial nitric oxide synthase gene polymorphisms in cardiovascular disease.
Vitamins and hormones - 1 Jan 2014
Vecoli Cecilia
Abstract excerpt
Endothelial nitric oxide synthase (eNOS or NOS3), an enzyme constitutively expressed especially in endothelial cells, is largely responsible for nitric oxide (NO) bioavailability at the endothelial level. Alterations in endothelial-derived NO production have been associated with various diseases, and, in humans, can be genetically determined by the presence of different polymorphisms in the eNOS gene. To date,...
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