Article
Allelic diversity at the merozoite surface protein-1 locus of Plasmodium falciparum in clinical isolates from the southwestern Brazilian Amazon.
The American journal of tropical medicine and hygiene - 1 Sept 1998
Ferreira M U, Liu Q, Kaneko O, Kimura M, Tanabe K, Kimura E A, Katzin A M, Isomura S, Kawamoto F
Abstract excerpt
Nucleotide sequences of each variable block in the Plasmodium falciparum merozoite surface protein-1 gene (PfMSP-1) may be grouped into one of two or three possible allelic types, named after the reference isolates MAD20, K1, and RO33. Allelic diversity at this locus basically results from different combinations of allelic types in variable blocks. We used a polymerase chain reaction (PCR)-based strategy to type...
Topics
- Adolescent
- Adult
- Alleles
- Animals
- Base Sequence
- Brazil
- Child
- Child, Preschool
- DNA, Protozoan
- Female
- Genetic Variation