Article
Definition of peptide binding motifs amongst the HLA-A*30 allelic group.
Tissue antigens - 1 Jul 2000
Krausa P, Münz C, Keilholz W, Stevanovic S, Jones E Y, Browning M, Bunce M, Rammensee H G, McMichael A
Abstract excerpt
HLA class I molecules present endogenously processed peptide ligands for surveillance by the T-cell receptor. This potentially immunogenic surface of HLA and peptide is a consequence of the polymorphism found within the HLA molecule and its preference for ligand binding together with peptide conformation within the binding groove. To investigate the relation between the polymorphic differences between some...
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