Article
Definition of specific peptide motifs for four major HLA-A alleles.
Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 1994
Kubo R T, Sette A, Grey H M, Appella E, Sakaguchi K, Zhu N Z, Arnott D, Sherman N, Shabanowitz J, Michel H
Abstract excerpt
Allele-specific motifs for the human MHC class I molecules, HLA-A1, A3, A11, and A24 were characterized by three complementary approaches. First, amino acid sequence analysis of acid eluted peptide pools from affinity purified class I molecules defined putative motifs 9 or 10 amino acids in length and bearing critical anchor residues at position 2 and at the COOH-terminal. These motifs were distinct, with the...
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