Article
Definition of specific peptide motifs for four major HLA-A alleles.
Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 1994
Kubo R T, Sette A, Grey H M, Appella E, Sakaguchi K, Zhu N Z, Arnott D, Sherman N, Shabanowitz J, Michel H
Abstract excerpt
Allele-specific motifs for the human MHC class I molecules, HLA-A1, A3, A11, and A24 were characterized by three complementary approaches. First, amino acid sequence analysis of acid eluted peptide pools from affinity purified class I molecules defined putative motifs 9 or 10 amino acids in lengt...
Topics
- Alleles
- Amino Acid Sequence
- Genes, MHC Class I
- HLA-A Antigens
- Humans
- Mass Spectrometry
- Molecular Sequence Data
- Peptides
- Protein Binding
- Structure-Activity Relationship