Article
Naturally processed HLA class I bound peptides from c-myc-transfected cells reveal allele-specific motifs.
Journal of immunology (Baltimore, Md. : 1950) - 1 Dec 1993
Harris P E, Colovai A, Liu Z, Dalla Favera R, Suciu-Foca N
Abstract excerpt
Naturally processed peptides, bound to HLA-A2, A68, B40 molecules, were isolated from a c-myc transfected lymphoblastoid B cell lines for sequence analysis. Forty-three sequences of bound peptides could be grouped into three structural motifs. One of the peptide sequences obtained, SLLPAIVEL, was identical to a previously reported peptide bound to HLA-A2.1 and was used for grouping HLA-A2-bound peptides. A second...
Topics
- Actins
- Alleles
- Amino Acid Sequence
- Antigen Presentation
- Base Sequence
- Cell Line, Transformed
- Cyclins
- Genes, myc
- Histocompatibility Antigens Class I
- Humans
- Molecular Sequence Data
