Article
The nature of peptides presented by an HLA class I low expression allele.
Haematologica - 1 Aug 2010
Hinrichs Jan, Föll Daniel, Bade-Döding Christina, Huyton Trevor, Blasczyk Rainer, Eiz-Vesper Britta
Abstract excerpt
BACKGROUND: The functional integrity of human leukocyte antigen low expression variants is a prerequisite for considering them as essential in the matching process of hematopoietic stem cell donors and recipients to diminish the risk of serious complications such as graft-versus-host disease or graft rejection. The HLA-A*3014L variant has a disulfide bridge missing in the alpha2 domain which could affect peptide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
