Article
Detailed motifs for peptide binding to HLA-A*0201 derived from large random sets of peptides using a cellular binding assay.
Human immunology - 1 May 1995
Drijfhout J W, Brandt R M, D'Amaro J, Kast W M, Melief C J
Abstract excerpt
Extensive sets of in total about 2000 synthetic peptides were investigated for their binding affinities to HLA-A*0201. Comparisons of the amino acid compositions of binding to nonbinding sets of peptides provided new information concerning the rules for 9-, 10-, and 11-mer peptide binding at the amino acid level. Preferred primary anchors were shown to depend on peptide length, longer peptides being more...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
