Article
Detailed motifs for peptide binding to HLA-A*0201 derived from large random sets of peptides using a cellular binding assay.
Human immunology - 1 May 1995
Drijfhout J W, Brandt R M, D'Amaro J, Kast W M, Melief C J
Abstract excerpt
Extensive sets of in total about 2000 synthetic peptides were investigated for their binding affinities to HLA-A*0201. Comparisons of the amino acid compositions of binding to nonbinding sets of peptides provided new information concerning the rules for 9-, 10-, and 11-mer peptide binding at the...
Topics
- Alleles
- Amino Acid Sequence
- Antigen Presentation
- Antigens, Neoplasm
- Antigens, Surface
- Cell Adhesion Molecules
- Cell Line
- Epithelial Cell Adhesion Molecule
- HLA-A Antigens
- Humans
- Molecular Sequence Data
- Papillomaviridae
- Peptides
- Protein Binding