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Article

Promiscuous CTL recognition of viral epitopes on multiple human leukocyte antigens: biological validation of the proposed HLA A24 supertype.

Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 2003

Burrows Scott R, Elkington Rebecca A, Miles John J, Green Katherine J, Walker Susan, Haryana Sofia M, Moss Denis J, Dunckley Heather, Burrows Jacqueline M, Khanna Rajiv

Abstract excerpt

Multiple HLA class I alleles can bind peptides with common sequence motifs due to structural similarities in the peptide binding cleft, and these groups of alleles have been classified into supertypes. Nine major HLA supertypes have been proposed, including an A24 supertype that includes A*2301, A*2402, and A*3001. Evidence for this A24 supertype is limited to HLA sequence homology and/or similarity in peptide...

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Identifiers

PMID: 12874232
DOI: 10.4049/jimmunol.171.3.1407

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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