Article
In the groove: the fine detail of antigen presentation to cytotoxic T lymphocytes.
Clinical science (London, England : 1979) - 1 Jun 1993
Moots R J
Abstract excerpt
1. A panel of cells designed to express normal or mutated human HLA-A0201 was constructed and used to investigate the interactions between the peptide antigen, class I major histocompatibility complex, CD8 and cytotoxic T lymphocyte antigen receptor. 2. Analysis of the extensive data generated has revealed that the optimum peptide presented to cytotoxic T lymphocytes by HLA-A0201 contains nine amino acids. It...
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