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Article

In the groove: the fine detail of antigen presentation to cytotoxic T lymphocytes.

Clinical science (London, England : 1979) - 1 Jun 1993

Moots R J

Abstract excerpt

1. A panel of cells designed to express normal or mutated human HLA-A0201 was constructed and used to investigate the interactions between the peptide antigen, class I major histocompatibility complex, CD8 and cytotoxic T lymphocyte antigen receptor. 2. Analysis of the extensive data generated has revealed that the optimum peptide presented to cytotoxic T lymphocytes by HLA-A0201 contains nine amino acids. It...

Topics

Amino Acid Sequence
CD8 Antigens
Epitopes
Genes, MHC Class I
HLA-A Antigens
Humans
Influenza A virus
Molecular Sequence Data
Mutation
T-Lymphocytes, Cytotoxic
Viral Matrix Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

beta 2-Microglobulin

Source

Identifiers

PMID: 7687528
DOI: 10.1042/cs0840585

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7687528-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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