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Article

Rad22 protein, a rad52 homologue in Schizosaccharomyces pombe, binds to DNA double-strand breaks.

The Journal of biological chemistry - 10 Nov 2000

Kim W J, Lee S, Park M S, Jang Y K, Kim J B, Park S D

Abstract excerpt

DNA double-strand breaks can be introduced by exogenous agents or during normal cellular processes. Genes belonging to the RAD52 epistasis group are known to repair these breaks in budding yeast. Among these genes, RAD52 plays a central role in homologous recombination and DNA double-strand break repair. Despite its importance, its mechanism of action is not yet clear. It is known, however, that the human...

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Identifiers

PMID: 10956666
DOI: 10.1074/jbc.M007060200

Genes

RAD52

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Rad22 protein, a rad52 homologue in Schizosaccharomyces pombe, binds to DNA double-strand breaks.PMID 10956666Read ↗

Schizosaccharomyces pombe Rad22A and Rad22B have similar biochemical properties and form multimeric structures.Semantic proximity Read ↗

Differential expression and requirements for Schizosaccharomyces pombe RAD52 homologs in DNA repair and recombination.Semantic proximity Read ↗

Role of RAD52 Epistasis Group Genes in Homologous Recombination and Double-Strand Break RepairSemantic proximity Read ↗

Control of Rad52 recombination activity by double-strand break-induced SUMO modification.Semantic proximity Read ↗

Rad52 Inverse Strand Exchange Drives RNA-Templated DNA Double-Strand Break Repair.Semantic proximity Read ↗

Human and yeast Rad52 proteins promote DNA strand exchange.Semantic proximity Read ↗

The Rad52 homologs Rad22 and Rti1 of Schizosaccharomyces pombe are not essential for meiotic interhomolog recombination, but are required for meiotic intrachromosomal recombination and mating-type-related DNA repair.Semantic proximity Read ↗

Interaction with Rad51 is indispensable for recombination mediator function of Rad52.Semantic proximity Read ↗

Role of the Rad52 amino-terminal DNA binding activity in DNA strand capture in homologous recombination.Semantic proximity Read ↗

Human RAD52 stimulates the RAD51-mediated homology searchSemantic proximity Read ↗

Reappearance from Obscurity: Mammalian Rad52 in Homologous RecombinationSemantic proximity Read ↗

Molecular Pathways: Understanding the Role of Rad52 in Homologous Recombination for Therapeutic AdvancementSemantic proximity Read ↗

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