Article
Differential expression and requirements for Schizosaccharomyces pombe RAD52 homologs in DNA repair and recombination.
Nucleic acids research - 15 Mar 2002
van den Bosch Michael, Zonneveld José B M, Vreeken Kees, de Vries Femke A T, Lohman Paul H M, Pastink Albert
Abstract excerpt
In fission yeast two RAD52 homologs have been identified, rad22A(+) and rad22B(+). Two-hybrid experiments and GST pull-down assays revealed physical interaction between Rad22A and Rad22B, which is dependent on the N-terminal regions. Interaction with Rhp51 is dependent on the C-terminal parts of either protein. Both Rad22A and Rad22B also interact with RPA. The expression of rad22B(+) in mitotically dividing...
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