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Article

Activated protein C resistance assay detects thrombotic risk factors other than factor V Leiden.

American journal of clinical pathology - 1 Jan 2003

Graf Laurie L, Welsh Carolyn H, Qamar Zainab, Marlar Richard A

Abstract excerpt

Activated protein C (APC) resistance is a common risk factor for venous thromboembolism (VTE) attributed to various mechanisms, including factor V Leiden (FVL) polymorphism. FVL is considered responsible for up to 95% of APC resistance; however, other factor V polymorphisms and elevated factor VIII levels also have been implicated. We assessed whether additional mechanisms contribute to APC resistance in a...

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Identifiers

PMID: 12520697
DOI: 10.1309/QCUU-NRMV-JY8M-WPPL

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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