Article
Comparison of three activated protein C resistance tests in the risk assessment of venous thrombosis in non-carriers of the factor V Leiden mutation.
Thrombosis and haemostasis - 1 Apr 2006
Guerrero Felipe, Arnaud Catherine, Nguyen Francoise, Boneu Bernard, Sié Pierre
Abstract excerpt
Activated protein C resistance (APCR), measured using the original assay described by Dahlbäck, is a risk factor for venous thrombosis independent of the factor V Leiden (FVL) mutation. This assay is based on the activated partial thromboplastin time (APTT) after plasma exposure to activated protein C (APC). As this assay was sensitive to numerous interferences, new assays have been developed for FVL screening....
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