Article
Enhanced detection and distinction of RNA by enzymatic probe ligation.
Nature biotechnology - 1 Jul 2000
Nilsson M, Barbany G, Antson D O, Gertow K, Landegren U
Abstract excerpt
It is important that RNA molecules representing members of gene families are distinguished in expression analyses, and even greater resolving power may be required to identify allelic variants of transcripts in order to investigate imprinting or to study the distribution of mutant genes in tissues. Ligase-mediated gene detection allows precise distinction of DNA sequence variants, but it is not known if ligases...
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