Article
Padlock Probes to Detect Single Nucleotide Polymorphisms.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018
Krzywkowski Tomasz, Nilsson Mats
Abstract excerpt
Rapid development of high-throughput DNA analyzation methods has enabled global characterization of genetic landscapes and aberrations in study subjects in a time and cost effective fashion. In most methods, however, spatial tissue context is lost since sample preparation requires isolation of nucleic acids out of their native environment. We hereby present the most recent protocol for multiplexed, in situ...
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