Article
<i>In vivo</i> formation of a proton‐sensitive K<sup>+</sup> channel by heteromeric subunit assembly of Kir5.1 with Kir4.1
1 Jun 2000
Abstract excerpt
Kir5.1 is an inwardly rectifying K+ channel (Kir) subunit, whose physiological function is unknown. Human embryonic kidney HEK293T cells co-transfected with rat Kir5.1 and Kir4.1 cDNA expressed a functional K+ channel, whose properties were significantly different from those of the homomeric Kir4.1 channel. Formation of a Kir4. 1/Kir5.1 assembly in HEK293T was confirmed biochemically. We found that heteromeric...
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