Article
ATP-sensitive potassium channels: a model of heteromultimeric potassium channel/receptor assemblies.
Annual review of physiology - 1 Jan 1999
Seino S
Abstract excerpt
ATP-sensitive K+ channels (KATP channels) play important roles in many cellular functions by coupling cell metabolism to electrical activity. By cloning members of the novel inwardly rectifying K+ channel subfamily Kir6.0 (Kir6.1 and Kir6.2) and the receptors for sulfonylureas (SUR1 and SUR2), researchers have clarified the molecular structure of KATP channels. KATP channels comprise two subunits: a Kir6.0...
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