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Article

Azathioprine associated T-cell mutations in insulin-dependent diabetes mellitus.

Scandinavian journal of immunology - 1 Jun 2000

Falta M T, Atkinson M A, Allegretta M, Vacek P M, Albertini R J

Abstract excerpt

Somatic mutations arise regularly in human T lymphocytes. As these events occur at increased frequencies in several autoimmune disorders, presumably because of increased T-cell proliferation, we investigated if this is also true for insulin-dependent diabetes mellitus (IDDM). Mutations of the hypoxanthine guanine phosphoribosyltransferase (hprt) gene measured by 6-thioguanine (TG) selection were studied in 28...

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Identifiers

PMID: 10849375
DOI: 10.1046/j.1365-3083.2000.00742.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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