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Article

T cells responsive to myelin basic protein in patients with multiple sclerosis.

Science (New York, N.Y.) - 9 Feb 1990

Allegretta M, Nicklas J A, Sriram S, Albertini R J

Abstract excerpt

Gene mutation in vivo in human T lymphocytes appears to occur preferentially in dividing cells. Individuals with multiple sclerosis (MS) are assumed to have one or more populations of diving T cells that are being stimulated by autoantigens. Mutant T cell clones from MS patients were isolated and tested for reactivity to myelin basic protein, an antigen that is thought to participate in the induction of the...

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Identifiers

PMID: 1689076
DOI: 10.1126/science.1689076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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T cells responsive to myelin basic protein in patients with multiple sclerosis.PMID 1689076Read ↗

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