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Article

Altered VH6-D-JH repertoire in human insulin-dependent diabetes mellitus and autoimmune idiopathic thrombocytopenic purpura.

European journal of immunology - 1 Sept 1999

Söderström I, van Dijk-Härd I, Feld S, Hillörn V, Holmberg D, Lundkvist I

Abstract excerpt

We have characterized the peripheral B cell repertoire in T cell-mediated insulin-dependent diabetes mellitus (IDMM) and in B cell-mediated autoimmune idiopathic thrombocytopenic purpura (AITP). The VH6-containing repertoire in adult patients with IDDM or AITP and healthy control subjects was investigated by PCR amplification using VH6- and JH-specific primers. Nucleotide sequence analysis of VH6-D-JH...

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Share to Diabetes Mellitus, Type 1
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Rearrangement, B-Lymphocyte

Share to Immunoglobulin Variable Region

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Share to Purpura, Thrombocytopenic, Idiopathic

Share to Receptors, Antigen, B-Cell

Source

Identifiers

PMID: 10508260
DOI: 10.1002/(SICI)1521-4141(199909)29:09<2853::AID-IMMU2853>3.0.CO;2-Y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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