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Article

The docking of primed vacuoles can be reversibly arrested by excess Sec17p (alpha-SNAP).

The Journal of biological chemistry - 28 Jul 2000

Wang L, Ungermann C, Wickner W

Abstract excerpt

Homotypic vacuole fusion occurs in ordered stages of priming, docking, and fusion. Priming, which prepares vacuoles for productive association, requires Sec17p (the yeast homolog of alpha-SNAP), Sec18p (the yeast NSF, an ATP-driven chaperone), and ATP. Sec17p is initially an integral part of the cis-SNARE complex together with vacuolar SNARE proteins and Sec18p (NSF). Previous studies have shown that Sec17p is...

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Identifiers

PMID: 10816559
DOI: 10.1074/jbc.M001447200

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NSF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The docking of primed vacuoles can be reversibly arrested by excess Sec17p (alpha-SNAP).PMID 10816559Read ↗

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Sequential action of two GTPases to promote vacuole docking and fusion.Semantic proximity Read ↗

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Sequential analysis of trans-SNARE formation in intracellular membrane fusion.Semantic proximity Read ↗

Sequential N- to C-terminal SNARE complex assembly drives priming and fusion of secretory vesicles.Semantic proximity Read ↗

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