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Article

Rho1p and Cdc42p act after Ypt7p to regulate vacuole docking.

The EMBO journal - 15 Oct 2001

Eitzen G, Thorngren N, Wickner W

Abstract excerpt

Rho GTPases, which control polarized cell growth through cytoskeletal reorganization, have recently been implicated in the control of endo- and exocytosis. We now report that both Rho1p and Cdc42p have a direct role in mediating the docking stage of homotypic vacuole fusion. Vacuoles prepared from strains with temperature-sensitive alleles of either Rho1p or Cdc42p are thermolabile for fusion. RhoGDI (Rdi1p),...

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Identifiers

PMID: 11598008
DOI: 10.1093/emboj/20.20.5650
PMCID: PMC125662

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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